The Kuskokwim 300, colloquially known as the "Kusko" or "K-300," stands as one of Alaska's prestigious mid-distance sled dog races, annually attracting top mushers in the sport. Originating in 1980, the race has been a January tradition, with an exception in 2021 when it was held in February to avoid coinciding with Super Bowl LV. The race, starting and concluding on the Kuskokwim River in Bethel, Alaska, runs along the river and its vicinity.

Historically, the Kuskokwim 300 pays homage to an early mail route connecting settlements along the river to the external world. This iconic race boasts a substantial purse of $160,000, making it the most lucrative 300-mile (480 km) sled dog race, attracting top mushers and hundreds of sled dogs annually.

Renowned for its challenging weather and trail conditions, the race has etched its mark in history. The inaugural race faced a formidable blizzard, accompanied by perilously low windchills in the initial leg, followed by an unexpected thaw and rain in the latter part. Notably, the 2008 race earned the moniker "Kusko-Swim" due to the presence of strong winds, rain, and deep overflow atop the river ice.

Early legends like Rick Swenson, Jerry Austin, Myron Angstman, and Rick Mackey set the race's prestigious tone. The 1990s showcased the dominance of Jeff King, Doug Swingley, and Martin Buser, paving the way for recent stalwarts like Pete Kaiser, who has won seven titles, including the latest in 2023.

• Starting line-Kuskokwim 300 sled dog race (CC 2.0)